Post on 02-Jun-2020
I Jornada: “Oportunidades de negocio en
nanotecnología”
NanoBioTer®
Maximizing polymer potential through flexible
nanotechnology
Contents
• About Us
• Technology
• Selected Data
• Production process and Products
Commercial Products
Products in Development
Customer Development
NanoBioTer ® - Material potential. Maximized.
About Us
Mission
To maximize plastics and bioplastics properties through unique, green and cost effective nanotechnology.
NanoBioTer® products
Nano-additives & concentrates for resin improvements (transparency, barrier, mechanical, thermal, rheological and active properties)
“Green” Values and Technology
Food contact approved (Complies with most stringent EU legislations)
Safe handling - nanoscale in only 1 dimension (after dispersion)
Naturally sourced raw materials (Nanoclays)
Focus on sustainable and biodegradable resins
Recyclable (and compostable) product
NanoBioTer ® - Material potential. Maximized.
About Us
Origin - Need for Combined Technologies
Founded in 2004 by Prof. Dr. Jose Maria Lagaron, Scientist with the CSIC, combining technologies from the fields of nanotechnology, food packaging, plastics reinforcement and biobased materials.
2008 - High Growth Company
• Unique patented technology Unique applications
• Group of shareholders composed by venture capital groups,
scientists and business angels.
• High academic level
• International workforce
NanoBioTer ® - Material potential. Maximized.
Structure
Medium Sized International Business
• Commercial Additive Plant - Vall D’Uixo, Spain
Capacity 2,500t/year ( 50,000-150,000t resin/year)
• Commercial extrusion plant – Valencia, Spain
(Under Construction / 2 months)
• Pilot Plants and Laboratory – Valencia, Spain
(Nanotechnology, plastics compounding, microbiology, barrier properties, food contact testing, thermal and mechanical plastics properties)
• Commercial offices: Spain (Valencia) and USA (Boston)
NanoBioTer ® - Material potential. Maximized.
Overview - Nanotechnology
Nanotechnology
nm
DNA
µm
Bacteria Bee Humans
mm m
Definition
Manufacturing of particles, products or devices with controlled particle size,
with at least 1 dimension below 0.1 microns (= 100 nanometers).
Property Microcomposite Nanocomposite
Young Modulus ↑ ↑
Toughness ↓↓↓ ↓ or neutral
Barrier properties ↓ ↑↑↑↑
Temperature resistance ↑ ↑↑
Transparency ↓↓↓ ↓
Cost ↓ ↑ or neutral
Common loading 20-50% 2-5%
Properties
Nanocomposites
Composite materials that incorporate nanofillers, typically below 10 wt.-%. The purpose
of a nanofiller is to enhance target properties while retaining most inherent
characteristics of the original matrix, such as transparency, toughness etc.
Nanoclay Modification
Surface
Modification
Mineral: Natural clay tactoid (stack) Modified Nanoclay
Nanoclay Platelet
Surface modifier
Nanoclay Dispersion
Intercalated Nanoclay Exfoliated Nanoclay
Nanoclay Platelet
Surface modifier
Polymer Chain
Physical Improvement & Active Solutions
Active Species
Nanoclay Platelet
Matrix:
Polymers, Ceramics, Solvents,
Other Substrates
Nanoclay – Matrix compatibilizer
Physical Improvement Active Functionality
Passive Barrier Properties, UV
Blocking, Thermal Properties,
Mechanical Properties.
Antimicrobial, Antioxidant and
Scavengers, Drug Control Release,
etc.
Tortuous Path Principle: Passive Barrier Enhancement
Physical Properties Improvement
O2 O2
Typical Barrier Improvement: Up to 1 order of magnitude
Without NanoBioTer® With NanoBioTer®
Active Properties
Higher efficiency than standard additives due to the exfoliated nano-system
Durability is ensured through permanent modification or controlled release mechanisms.
Without NanoBioTer+® With NanoBioTer+®
Novel properties through functionalization of the nanoadditives
Selected Data
Conventional Polymers and Biopolymers
Oxygen Barrier: EVOH + NanoBioTer®
O2 Barrier
NanoBioTer® decreases oxygen
permeability approx. 70% at
elevated humidity conditions
(m3·m
)/(m
2·s
·Pa
) · 1
0-2
0
Water activity (humidity)
Oxygen Permeability
0
0,2
0,4
0,6
0,8
1
1,2
0,9 0,8
EVOH 32
EVOH 32 + NanoBioTer
JM Lagaron et al., Food Additives and Contaminants, 22 (10), pp. 994-998, 2005
EVOH neatEVOH + 4% NanoBioTer®
NanoBioTer ®: High transparency
Transparency: EVOH + NanoBioTer®
Oxigen Permeability
Limonene Permeability
0
1
2
3
4
1
PET
NanoPET
P(m
3m
/m2·s
·Pa
)·10
-19
0
1
2
3
4
5
1
PET
NanoPET
LT
R (
Kg·m
/s·m
2)·
10
-16
O2 Barrier
PET is generally regarded as highly
sensitive to process conditions and
humidity.
NanoBioTer ® products enable enhanced
barrier properties, when combining
optimum surface modification and process
parameters.
Oxygen Barrier: PET + NanoBioTer®
JM Lagaron et al., Journal of Plastic & Film Sheeting 23 (2) 133-148, 2007
Biopolymers – Definition
Biopolymers (sustainable)
Biopolymers are materials obtained from renewable biomass feedstocks, such as corn, potato, etc., and therefore have a reduced impact in the accumulation of greenhouse gases and on the well-known carbon footprint.
Examples of Biopolymers: PLA, PHB, Chitosan, etc.
Biodegradable polymers
Biodegradable polymers are materials designed to biodegrade into carbon dioxide and water upon disposal by the action of soil microorganisms and water. The degradation must take place in a limited timeframe.
O2 Barrier
PLA
NanoBioTer® enables reduction of
oxygen permeability in the range
of 40-90%. Typical value 50%
improvement.
PHB
NanoBioTer® enables reduction of
oxygen permeability in the range
of 40-90%. Typical value 50%
improvement.
PHB + NanoBioTer® exhibit
barrier properties that are
comparable to PET.
Oxygen Permeability
0
0,5
1
1,5
2
2,5
1
PHB
NanoPHB
PLA
NanoPLA
PET
NanoPET
PHB PET
PLA
P(m
3m
/m2·s
·Pa
)·10
-18
Biopolymers + NanoBioTer®
JM Lagaron et al., Journal of Plastic & Film Sheeting, 23 (2) 133-148, 2007
JM Lagaron et al., Journal of Plastic & Film Sheeting, 22 (4), pp. 265-274, 2006
Transparency: PLA + NanoBioTer®
NanoBioTer ®: High Transparency
PLA neatPLA
+ 5% NanoBioTer®
Thermal properties
2D Graph 6
Temperatura (ºC)
250 275 300 325 350 375
Pé
rdid
a M
asa
(%
)
70
80
90
100 TGA
Temperature (ºC)
Loss M
odulu
s (P
a)
Bioresin
Bioresin 5% NanoBioTer 1
Bioresin 5% NanoBioTer 2
Temperature (ºC)
DMA
NanoBioTer® enables increased HDT (Heat Deflection Temperature) performance in biopolymers
such as PLA*. This is an important characteristic for these materials with generally limited thermal
resistance (softening begins above 40ºC.)
NanoBioTer® delays the onset of thermal degradation, as illustrated by the TGA curve (Thermal
Gravimetric Analysis).
* The exact conditions and improvement is protected under customer confidentiality agreement
PHB blend + 4% market nanoclay
PHB blend + 4%NanoBioTer®
PHB blend
Process Stability
NanoBioTer® has a very low impact on the processing degradation of the
polymer. The polymer structure, as reflected by the melting point, is largely
retained (this is not the case for other traditional nanoclays offered on the
market)
JM Lagaron et al., Journal of Applied Polymer Science, 108 (5), 2787-2801, 2008
UV Protection: PLA + NanoBioTer®
* Patent pending
Increasing Content NanoBioTer®
0
10
20
30
40
50
60
70
80
90
100
PLA Original
Tra
nsm
itta
nce a
t 3
00
nm
( %
)
Transmittance at 300nm (30 microns Film)*
UV Protection
NanoBioTer® has unique, UV
blocking properties.
This technology allows
protection of packaging
contents while maintaining
transparency.
Barrier Coatings
0,0E+00
2,0E-08
4,0E-08
6,0E-08
8,0E-08
1,0E-07
1,2E-07
1,4E-07
1,6E-07
1 2
Biopolymer
standard coating
Biopolymer with
NanoBioTer® coating
Water Vapour Transmision Rate
WV
TR
(g
m /
s m
2)
H2O Barrier
NanoBioTer® is a highly
efficient coating additive.
Example: Water sensitive
protein film.
JM Lagaron et al., SPE Antec 2008 Conference Proceedings, USA, 2008
Antimicrobial additives
High efficiency and duration through controlled release mechanism
Active Properties
NanoBioTer+® Antimicrobial activity tested as per specification in
JIS Z 2801 and ISO 22196:2007 norms.
Without
antimicrobial
additive
NanoBioTer+®
antimicrobial
additive
S.Aureus bacteria
Gelatin film with
chlorophyllin E-140
NanoBioTer® - Process and Products
NanoBioTer® Process
+
Purification
ProcessSurface
Modification
NanoBioTer ®
NanoBioTer ®
Concentrates
Extrusion
Process
Raw Clay Nano Clay
NanoBioTer ® Resin
Products
NanoBioTer® Barrier Additives
• Gases O2, CO2
• Water Vapor
• Aromas
• Migrants
- Up to 1 order of magnitude improvement
Focus systems – Packaging (Food) – Increasing shelf-life
• High barrier / multilayer systems (e.g.. EVOH).
• Biodegradable / Sustainable resins (e.g.. PCL, PHB)
• Coatings (Casting, extrusion coating, lamination)
• Transparent packaging materials (e.g.. PET)
Development Partnership
Efficiency is highly dependent on processing conditions, so materials
should always be tested in the industrial application.
• UV light
• Chemical
• Oil and Grease
NanoBioTer ® - Material potential. Maximized.
Products - Active +
NanoBioTer+® Active Antimicrobial Properties combined with barrier performance for a wide range of applications
• Water and solvent based coatings
• Powder coatings
• Gel coats
• Paints
• Packaging
• Surfaces
Norm Compliant: JIS Z 2801 and ISO 22196:2007
NanoBioTer ® - Material potential. Maximized.
Products – Next Generation
NanoBioTer® Developments
Short term
• Additional active additives NanoBioTer+®
(e.g. antioxidants and other active/bioactive components)
• Additives for a wider range of resins through unique patent-pending modification techniques
• Increased product efficiency through unique patent-pending production steps.
Medium Term
• Reinforcing nanoadditives for resorbable and permanent plastic implants in biomedical applications
• Controlled/accelerated biodegradability
NanoBioTer ® - Material potential. Maximized.
Customer Projects and
Developments
Flexible NanoBioTer® technology
Improvements in an extremely wide range of applications, resins and properties:
• Targeting specific properties for a customer application
• Physical and chemical modification to obtain maximum dispersion in nearly any polymeric system
• Extensive lab and pilot plant equipment for development and testing purposes
Your partner for project management
We work actively with your team to cover all aspects of a successful development:
• Determine objectives and regulatory needs according to application
• Set timing for development steps and milestones
• Identify “what” to measure and “how”
• Determine ownership rights for the developed properties and products
• Finalize project plan and costs
• Create synergies for product marketing and launch
NanoBioTer ® - Material potential. Maximized.
Contact
Business Development DirectorOle Faarbaek Jensen
ofaarbaek@nanobiomatters.com
Research & Development DirectorProf. Dr. Jose Maria Lagaron
lagaron@nanobiomatters.com
Phone: +34 961 31 86 28
NanoBioTer ® - Material potential. Maximized.
Thank you for your attention…
NanoBioTer ®
- Tomorrows Technologies, Combined Today