7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

1/24

Gmoki`sgls bs`ols dm ck

e`s`lclhk rmsp`rktlr`k

Dr. G`ojkmc Kyudkit Rkgls_mdm Jlsp`tkc _ki FlsOkcckl

]^_FB

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

2/24

Euio`lims dm ck rmsp`rko`i

;. Umit`cko`i pucglikr

2. D`eus`i dm lxhmil y d`x`dl dm okrblilmitrm cls kcvmlcls y ck skihrm.

?. Trkisplrtm dm lxhmil y d`x`dl dm okrblilmitrm cls kcvmlcls y ck skihrm.

4. Rmhucko`i dm ck vmit`cko`i y ltrls kspmotlsdm ck rmsp`rko`i.

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

3/24

Rlc e`s`lch`ol dm cls pucglims

Gkitmimr mc lxhmil d`spli`bcm k cls tmf`dls.

Rmglvmr d`x`dl dm okrblil prlduo`dl.

Glv`g`mitl dm k`rm `isp`rkdl jko`k mc cmojlokp`ckr pucglikr@itmrokgb`l dm hksms.

Mstl sm rmkc`zk6 Oli gi`gl mseumrzl.

Oli rmhucko`i guy me`o`mitm smhi ck dmgkidk. Oli s`iorlik kdmoukdk mitrm vmit`cko`i y

pmreus`i.

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

4/24

O`erks dm ck vmit`cko`i pucglikr

Mi rmplsl6

^ucglims tlgki 4 C/g`i dm k`rm y = C/g`i dmskihrm

Oli mfmro`o`l gx`gl6

^ucglims pumdmi tlgkr jkstk ;>> C/g`i dm k`rm y2= C/g`i dm skihrm.

Olitrlc dm mstk tkrmk pr`io`pkcgmitm iloliso`mitm

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

5/24

Kiktlgk dmc s`stmgk rmsp`rktlr`l

_`stmgk rmsp`rktlr`l gkdurl6

Elsks ikskcms

Ekr`ihm y ckr`ihm okrtckhl or`ol`dms (cg`tm)

Trqumk

^ucglims oub`mrtls plr pcmurk v`somrkc

D`kerkhgk6 ^r`io`pkc gsoucl pkrk ck vmit`cko`i

_`stmgk brliqu`kc6 2? hmimrko`lims

Tmf`dl kcvmlckr6 rmk 8= g2.

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

6/24

Gsoucls rmsp`rktlr`ls

@isp`rko`i kot`vk

Msp`rko`i pks`vk

D`kerkhgk6 Mc pr`io`pkc

@itmrolstkcms

^krk mcmvkr olst`ccks `iemr`lrms

Gsoucls koomslr`ls Mseumrzl

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

7/24

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

8/24

_`stmgkbrliqu`kc6

Hmimrko`limsdm oliduotlsbrliqu`kcms

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

9/24

Kcvmlcls

Kcvmlcl6 ]i`dkd euio`likc dmc pucgi]i`dl kcokp`ckr y mstruoturk kdykomitm (`itmrst`o`l).

^rlomsls e`s`lch`ols6

Umit`cko`i6 K`rm `ihrmsk dmsdm mc mxtmr`lr jkstk mckcvmlcl y gs tkrdm skcm dm iumvl kc mxtmr`lr.

D`eus`i6 @itmrokgb`l dm cls hksms mitrm mc kcvmlcl y mcokp`ckr pucglikr.

^mreus`i6 ^ksl dm skihrm plr mc okp`ckr. Mst skihrm vkk smr ck qum sm lx`hmik y gs tkrdm vumcvk kc olrkzi.

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

10/24

Umit`cko`i kcvmlckr

2=% k`rm `isp`rkdl il pkrt`o`pk dmc`itmrokgb`l (UK oliduoo`i)

Mspko`l gumrtl kiktg`ol

Ut`dkctltkc7 Ugumrtl + U kcvmlckr

Hrkd`mitm Kk (^KL2- ^kL2)

Dmtmotk dmemotls dm lx`hmiko`i

Ilrgkc6 =-;= ggJh

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

11/24

K6 KcvmlclKD6 DuotlkcvmlckrRB6 Brliqu`lclrmsp`rktlr`lTB6 Brliqu`ltmrg`ikc

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

12/24

_urekotkitm

^rlduo`dl plr cks ocuckskcvmlckrms t`pl @@

Olgpumstl plr elselcp`dls(d`pkcg`tl`celsekt`d`colc`ikQD^^OW)y prltmiks mspmoe`okskslo`kdks.

Rmduom tmis`i supmre`o`kcslbrm mc mp`tmc`l kcvmlckr

mxpkis`i kcvmlckr oli prms`idm d`stmis`i 3 = og J2L.

_`i mstk okpkCk msp`rko`iprlduo`rk olckpsl kcvmlckr

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

13/24

@itmreksm kcvmlcl - okp`ckr

Trkisplrtm L2

]i`dl k Jb (ck gkylrk)

D`sumctl mi mc pcksgk

Ourvk dm d`slo`ko`i L2-Jb

K dmr6 ke`i`dkd, 9 mitrmhk

K `zq6 ke`i`dkd, 3 mitrmhk

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

14/24

@itmrokgb`l dm hksms

Trkisplrtm dm lxhmil kc okp`ckr

D`eus`i `itmreksm Kk

Trkisplrtm ui`dl k Jb / d`sumctl mi mc pcksgk

D`eus`i `itmreksm Kk

Cmy E`oa

D`eus`i dm hksms ms prlplro`likc kc rmk dm

`itmrokgb`l y k ck d`emrmio`k dm prms`lims dmc hks (L2yOL2)

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

15/24

@itmrokgb`l dm hksms

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

16/24

@itmrokgb`l dm hksms Mqu`c`br`l mitrm ck vmit`cko`i pucglikr (U) y mc ecufl

skihuiml okp`ckr ([) Rmcko`i vmit`cko`i pmreus`i (U/[)

]i`dkd euio`likc kcvlcl okp`ckr

Oliolrdkio`k pmremotk U/[ 7 ;

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

17/24

Trkisplrtm dm OL2

D`sumctl mi ckskihrm =%

Olgl

B`okrbliktl(JOL?-) 0>%

Oli Jb,Okrbkg`il -OL2=%

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

18/24

Olitrlc dm ck rmsp`rko`i

Rmkc`zkdk plr mc _IO6

Rmomptlrms k i`vmc dmc bucbl rkqudml (omitrlrmsp`rktlr`l)6

[u`g`lrrmomptlrms6 _mis`bcms k i`vmcms dm OL2,smis`bcms kc pJ y smis`bcms kc L2.

Rmomptlrms gmoi`ols6 ^ucglims, guolsks, okfktlro`okv`kfk k trkvs dmsdm cks vks gltlimurlikcms

pkrk ccmhkr k gsoucls rmsp`rktlr`ls y kc d`kerkhgk.

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

19/24

_`stmgk imrv`lsl pucglikr

E`brks imrv`lsks pkrks`gpt`oks (vkhkcms),s`gpt`oks, y mc s`stmgk il kdrmirh`olilolc`irh`ol (IKIO).

E`brks memrmitms6 ^krks`gpt`oks6 Olc`irh`oks gusokri`oks

brliololistr`oo`i, vksld`cktko`i pucglikr ysmormo`i guolsk

_`gpt`oksrmckfko`i dm gsoucl c`sl brliqu`kc,

vkslolistr`oo`i pucglikr m `ij`b`o`i dm smormo`lims _`stmgk IKIO6 Trkisg`slrms olgl KT , x`dl itr`ol y

IT olgl sustkio`k ^ y U@^ mvmitls `ij`b`tlr`ls .

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

20/24

E`brks kemrmitms pucglikrms6

Dm rmomptlrms dm d`stmis`i brliolpucglikr (trqumky brliqu`ls prlx`gkcms)K ck `iecko`i, prlduomi

brliold`cktko`i y kugmitl dm ck E.O. Dm rmomptlrms `rr`tkitms (vks prlx`gkcms)Tls,

brliololistr`oo`i y smormo`i dm glol.

E`brks O l rmomptlrms yuxtkokp`ckrms (F) (pkriqu`gk y

pkrmd brliqu`kc)Mstgucls gmoi`ols y qug`olsokgb`l mi pktri rmsp`rktlr`l, smormo`i dm glol,tls y d`sg`iuo`i dm E.O. oli ck `isp`rko`i.

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

21/24

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

22/24

E@_@LCLHK DM CK UMIT@CKO@I

^]CGLIKR

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

23/24

Ulcgmims y okpko`dkdms pucglikrms

Ulcugmi dm hks pucglikr6 D`v`d`dl mi vlcgmims y okpko`dkdms Ulcgmims il sm supmrplimi uil kc ltrl

Ulcugmi t`dkc (UT)6 Okit`dkd dm hks `ijkckdl y mxjkckdl miokdk rmsp`rko`iKprlx ?=>4>> gC (8> ah).

Ulcugmi rms`dukc (RU)6 Okit`dkd dm hks rmstkitm mi clspucglims kc e`ikc dm ck msp`rko`i gx`gk

Okpko`dkdms pucglikrms6 Olgpumstks plr 2 l gs vlcgmims

Okpko`dkd v`tkc (OU)6 Okit`dkd dm hks qum pumdm mxjkckrsm

dmspus dm uik `ijkcko`i gx`gk. Okpko`dkd pucglikr tltkc (O^T)6 Okpko`dkd v`tkc + vlcugmi

rms`dukc6 Okit`dkd tltkc dm hks kc e`ikc dm ck `ijkcko`i gx`gk.

Okpko`dkd rms`dukc euio`likc (ORE)6 Okit`dkd dm hks mi cls

pucglims kc e`ikc dm uik rmsp`rko`i mi rmplsl

7/21/2019 5-Mecanismos Bsicos de La Fisiologa Respiratoria UPSJB

24/24

Msp`rlhrkgk

O^T

OU

UR

O@

ORE

UR@

URM

UR

@isp`rko`i gx`gk

I`vmc rmsp`rktlr`lmi rmplsl

Msp`rko`i gx`gk