Echokardiographie in der HD...1 Moller et al. Left atrial volume: a powerful predictor of survival...

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Stephan Heyl Medizinische Klinik III- Kardiologie Universittsklinikum Frankfurt Echokardiographie in der HD

Transcript of Echokardiographie in der HD...1 Moller et al. Left atrial volume: a powerful predictor of survival...

Page 1: Echokardiographie in der HD...1 Moller et al. Left atrial volume: a powerful predictor of survival after acute myocardial infarction. Circulation 2003;107:2207-12. 2 Modena et al Left

Stephan HeylMedizinische Klinik III- Kardiologie

Universitätsklinikum Frankfurt

Echokardiographie in der HD

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Überblick

Das kardiorenale Syndrom

RCS- heart and kidney in patients in dialysis facilities

Echokardiographische Befunde und Parameter

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�Disorders of the heart and kidneys whereby acute or chronic dysfunction may induce acute or chronic dysfunction in the other�

C. Ronco, P. McCullough, S. D. Anker, et al., �Cardio-renal syndromes: an executive summary from the consensus conference of the Acute Dialysis Quality Initiative,� Contributions to Nephrology, vol. 165, pp. 54�67, 2010.

Das kardiorenale Syndrom

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CRS Typ I (akut)

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CRS Typ II (chronisch)

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Das kardiorenale Syndrom

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Goals Point prevalence of

CRS Describe

treatment patterns Evaluate physician

awareness

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Der Left Atrial Volume Index (LAVI)

Korrelation LA Volumen und Mortalität nach Myokardinfarkt , DCM und Patienten mit Peritonealdialyse

1 Moller et al. Left atrial volume: a powerful predictor of survival after acute myocardial infarction. Circulation 2003;107:2207-12.2 Modena et al Left atrial size is the major predictor of cardiac death and overall clinical outcome in patients with dilated cardiomyopathy: a long-term follow-up study. Clin Cardiol 1997;20:553-60.3 Kim et al. �Left Atrial Volume Is an Independent Predictor of Mortality in CAPD Patients�. Nephrology Dialysis Transplantation 26, Nr. 11 3732�3739.

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Bestimmung des LAVI Bestimmung erfolgt gemäß den

Richtlinien der ESC/ ASE Zwei Methoden

Errechnung nach der �area length� Methode

Biplan, modifiziert nach Simpson

Indizierung des Volumens auf die Körperoberfläche

Lang et al. �Recommendations for chamber quantification�. European journal of echocardiography: the journal of the Working Group on Echocardiography of the European Society of Cardiology 7, Nr. 2 (März 2006): 79�108.

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LV Masse

The RT3D data resulted in significantly larger LV long-axis dimensions and measurements of LV mass that correlated with CMR better (r0.90) than 2D (r0.79). The 2D technique underestimated LV mass (bias, 39%), whereas RT3D measurements showed only minimal bias (3%). The 95% limits of agreement were significantly wider for 2D (52%) than RT3D (28%). Additionally, the RT3D technique reduced the interobserver variability (37% to 7%) and intraobserver variability (19% to 8%).

Circ 2004;110;1814-18

VielversprechendeStudien

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Mitralringverkalkung3DE Empfohlen

10-50% der Patienten mit ESRD

Risikofaktoren Sekundärer Hyperpara Alter/ Dauer der HD

Raggi P, Bommer J, Chertow GM. Valvular calcification in hemodialysis patients randomized to calcium-based phosphorus binders or sevelamer. J Heart Valve Dis 2004; 13:134.

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Kalzifizierte Aortenklappenstenose3DE Empfohlen

15-20 % der Patiententen, bei 3-9% hochgradig

Schnelles Fortschreiten (0,23cm² versus 0,05- 0,1 cm²)

Baglin A. et al, Severe valcular heart disease in patientts on chronic dialysis, Ann Med Interne, 1997, 148:521

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Pulmonale Hypertonie3DE Empfohlen

Prävalenz 17-49% Geringer unter

Peritonealdialyse? Spezifische Therapie?

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Klappeninsuffizienzen und Hämodialyse3DE Empfohlen

Prävalenz von Klappeninsuffizienzen hoch

Vor Echo Gewichtsoptimierung sinnvoll

K/DOQI Workgroup. K/DOQI clinical practice guidelines for cardiovascular disease in dialysis patients. Am J Kidney Dis 2005; 45:S1.

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Vielen Dank für Ihre Aufmerksamkeit !

Echokardiographie -Labor:

PD Dr. Birgit AßmusAngie Schmitt & Christine Scheld

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