Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective...

33
RECONOCIMIENTO RESPUESTA

Transcript of Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective...

Page 1: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

RECONOCIMIENTO RESPUESTA

Page 2: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

LA INMUNIDAD INNATA

Cada tipo celular responderá en función de sus propias capacidades

Page 3: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 4: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

¿ QUÉ RECONOCEN LAS CÉLULAS DE LA INMUNIDAD INNATA?

PATRONES MOLECULARES ASOCIADOS A PATÓGENOS

¿ CÓMO LOS RECONOCEN ?

PATRONES MOLECULARES ASOCIADOS A DAÑO

A TRAVÉS DE LOS RRP

Page 5: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 6: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

¿ QUÉ RECONOCEN LAS CÉLULAS DE LA INMUNIDAD ADAPTATIVA?

ANTÍGENOS

RECEPTOR B o BCR RECEPTOR T o TCR

Page 7: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

¿ CUÁNTOS RECEPTORES HAY ?

Page 8: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

¿ CÓMO SE GENERAN LOS RECEPTORES ?

RECOMBINACIÓN SOMÁTICA

Page 9: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

¿DÓNDE GENERAN SUS RECEPTORES LOS LINFOCITOS T Y B Y CÓMO SE LLAMA ESE PROCESO?

Page 10: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 11: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 12: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 13: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 14: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 15: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

¿ QUÉ TIENE DE ESPECIAL LA INMUNIDAD ADAPTATIVA?

Page 16: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

PRIMER ENCUENTRO CON UN ANTÍGENO

Page 17: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

SEGUNDO ENCUENTRO CON UN ANTÍGENO

Page 18: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 19: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

A MEDIDA QUE PASA EL TIEMPO, LA CANTIDAD DE LINFOCITOS QUE

RESPONDEN A UN ANTÍGENO ESPECÍFICO , AUMENTA

LA PROBABILIDAD DE QUE SE DE EL ENCUENTRO CON EL ANTÍGENO ES CADA VEZ MAYOR Y MÁS RÁPIDA.

EXPANSIÓN CLONAL

MEMORIA

Page 20: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

LOS LINFOCITOS B RECONOCEN EL ANTÍGENO DE FORMA SOLUBLE

Page 21: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

NO OCURRE LO MISMO PARA LOS LINFOCITOS T

Page 22: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

CMH I CMH II

Page 23: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

MUCHOS PATÓGENOS REPLICAN DENTRO DE LAS CÉLULAS

PRESENTACIÓN POR CMH I

Page 24: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 25: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 26: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

POLIMORFISMOS

Page 27: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 28: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

Zinkernagel, Rolf Martin

EXPERIMENTO

Peter Doherty

http://dic.idiomamedico.net/Zinkernagel,_Rolf_Martin
http://dic.idiomamedico.net/Zinkernagel,_Rolf_Martin
http://dic.idiomamedico.net/Zinkernagel,_Rolf_Martin
http://dic.idiomamedico.net/Zinkernagel,_Rolf_Martin
http://dic.idiomamedico.net/Zinkernagel,_Rolf_Martin
Page 29: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

RESTRICCIÓN POR CMH

Page 30: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

POLIMORFISMO Y ENFERMEDAD CELÍACA

Page 31: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 32: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.
Page 33: Presentación de PowerPoint · ERp57) and binds to TAP via tapasin Cytosolic proteins md defective ribosomal products (DRiPs) are degraded to peptide fragnEnts by the proteasome.

RNA ribosomal traduciendo

RNA ribosomal traduciendo

To mock or not to mock

To mock or not to mock

Yo Go verbs Un repaso…. GO verbs tener (to have) hacer (to make, to do) salir (to go out, to leave) poner (to put, place, set) venir (to come) traer (to.

Yo Go verbs Un repaso…. GO verbs tener (to have) hacer (to make, to do) salir (to go out, to leave) poner (to put, place, set) venir (to come) traer (to.

STAND PUBLICITARIOS - GonneiPublicidad · Et presente diseñoe+ ad intelectu . TO ZLCCTrlC TO euccmc TO euecrnc TO TO de TO ZLCCTrlC TO atacrrlc . Brindamos soluciones para sus comunicaciones

STAND PUBLICITARIOS - GonneiPublicidad · Et presente diseñoe+ ad intelectu . TO ZLCCTrlC TO euccmc TO euecrnc TO TO de TO ZLCCTrlC TO atacrrlc . Brindamos soluciones para sus comunicaciones

Ayuntamiento de Salamanca - Sede Electrónica - Presentación€¦ · 1.745 2.933 3.225 PSÍCOTÉCNICO A p TO A p TO A p TO A p TO AF)TO FISICAS A p TO APTO A p TO AID TO AID TO TEORICO

Ayuntamiento de Salamanca - Sede Electrónica - Presentación€¦ · 1.745 2.933 3.225 PSÍCOTÉCNICO A p TO A p TO A p TO A p TO AF)TO FISICAS A p TO APTO A p TO AID TO AID TO TEORICO

Estudio del gen del ARN ribosomal 23S

Estudio del gen del ARN ribosomal 23S

PulmoBind, an Adrenomedullin-Based Molecular Lung …espace.inrs.ca/2942/1/Journal of Nuclear Medicine.pdfAM1 over AM2 (CRLR/Ramp3) (6,14). Thus, this peptide appeared has a good starting

PulmoBind, an Adrenomedullin-Based Molecular Lung …espace.inrs.ca/2942/1/Journal of Nuclear Medicine.pdfAM1 over AM2 (CRLR/Ramp3) (6,14). Thus, this peptide appeared has a good starting

to y to Ambiental

to y to Ambiental

ARN polimerasas procariontes - UABCpeces.ens.uabc.mx/bcym/clases/pdf/IVd Transcripcion.pdf · ARN polimerasas • RNA polimerasa I (RNA Pol I): Transcribe RNA ribosomal (RNAr) de

ARN polimerasas procariontes - UABCpeces.ens.uabc.mx/bcym/clases/pdf/IVd Transcripcion.pdf · ARN polimerasas • RNA polimerasa I (RNA Pol I): Transcribe RNA ribosomal (RNAr) de

1. 2 Objetivos: Evidenciar un mecanismo de silenciamiento traduccional que implica la liberación de una proteína integral ribosomal. Proponiendo así,

1. 2 Objetivos: Evidenciar un mecanismo de silenciamiento traduccional que implica la liberación de una proteína integral ribosomal. Proponiendo así,

Episodio - Vista Higher Learning€¦ · comer hamburguesas to eat hamburgers regalos gifts correr to run, to jog salir* a cenar to go out to dinner discutir (de/con) to discuss,

Episodio - Vista Higher Learning€¦ · comer hamburguesas to eat hamburgers regalos gifts correr to run, to jog salir* a cenar to go out to dinner discutir (de/con) to discuss,

La Comida Peruana 3.7.06- 3.8.06 Define 1.Cortar: 2. Mezclar: 3. Poner: 4. Añadir: 5. Hervir: 6. Comer: to cut to mix to put to add to boil to eat.

La Comida Peruana 3.7.06- 3.8.06 Define 1.Cortar: 2. Mezclar: 3. Poner: 4. Añadir: 5. Hervir: 6. Comer: to cut to mix to put to add to boil to eat.

-er & -ir verbos · •Creer •Beber •Aprender •Leer •Ver •Poner •Hacer •Abrir •Vivir •Escribir •Salir •To eat •To believe •To drink •To learn •To read

-er & -ir verbos · •Creer •Beber •Aprender •Leer •Ver •Poner •Hacer •Abrir •Vivir •Escribir •Salir •To eat •To believe •To drink •To learn •To read

Decoding the ribosomal arn chromosome 16s

Decoding the ribosomal arn chromosome 16s

E-> ie verbos- ¿Qué es…? To think /plan To prefer To come To want Pensar Preferir Venir querer.

E-> ie verbos- ¿Qué es…? To think /plan To prefer To come To want Pensar Preferir Venir querer.

Rna Ribosomal

Rna Ribosomal

Antibióticos que inhiben la síntesis proteica ribosomal

Antibióticos que inhiben la síntesis proteica ribosomal

Peptide Growth Factors and Their Receptors II

Peptide Growth Factors and Their Receptors II

Let’s review the verbs. to have fun To see (ver) To order (pedir) To take (tomar/sacar) To visit (visitar) To get sick (enfermarse)

Let’s review the verbs. to have fun To see (ver) To order (pedir) To take (tomar/sacar) To visit (visitar) To get sick (enfermarse)

Hacer to do / to make hago. salir to leave / to go out salgo.

Hacer to do / to make hago. salir to leave / to go out salgo.