1. Parte 1
LA PIEL
2. GENERALIDADES
3. QUE ES LA PIEL?
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
6. LA PIEL EN NMEROS
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
13. COMPLEJIDAD DE LA PIEL
En un cm2 de piel hay:
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
20. VARIACIONES DE LA PIEL
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
23. ESTRATOS EPICUTANEOS
Microatmsfera que rodea la piel del individuo y lo pone en contacto
con el medio exterior y son:
1.-Manto gaseoso : Capa de aire mas caliente con mas contenido de
C0 2 y vapor de agua resultante de la evaporacin del agua.
2.-Manto cido : Emulsin de la secresinsudoral y sebcea. pH 5.5. (C0
2 y aminocidos). Ventanas alcalinas
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
24. COMPONENTES QUIMICOS DE LA PIEL
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
31. FISIOLOGA DE LA PIEL
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
43. 1.ANATOMA.
EPIDERMIS
DERMIS
HIPODERMIS
FANERAS O
ANEXOS
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
44. SUPERFICIE DE LA PIEL
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
50. A. EPIDERMIS
E. crneo
E. lcido
E. granuloso
E. espinoso
E. germinativo o basal
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
51. Estrato basal o germinativo.
Capa proliferante.
Clula basaloide
Mitosis
Melanocitos.
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
52. Estrato espinoso
Estrato granuloso
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
53. Estrato crneo.
Capa ms superficial.
Son clulas muertas, aplanadas, sin ncleo y queratinizadas.
En las reas sometidas a presiones y roces ( palmoplantares ) es ms
grueso, mientras que en el resto de la piel es ms delgado y
flexible.
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
54. OTRAS CLULAS
Melanocitos
Clulas dendrticas
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
55. Clulas de Merkel
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
57. B. DERMIS
D. PAPILAR:
Huellas digitales
D. RETICULAR:
Redes de colgeno
Tejido conjuntivo denso
Vasos sanguneos.
Vasos linfticos.
Msculos
Terminaciones nerviosas
Anexos cutneos:
Folculos pilosos
Glndulas
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
58. Tejido conectivo y clulas adiposas: ADIPOCITOS.
Tambin: TEJIDO CELULAR SUBCUTNEO O PANCULO ADIPOSO.
C. HIPODERMIS:
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
59. D. ANEXOS CUTNEOS
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
66. PELO
PELO: (Mdula y cutcula)
RAIZ (Bulbo)
TALLO
MSCULO ERECTOR
GLNDULA SEBCEA
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
67. 2. FISIOLOGA:
TERMORREGULACIN
ABSORCIN
PROTECCIN
Microorganismos
Traumatismos
Agentes extraos
Radiacin UV.
EXCRECCIN
SENSORIAL
SECRECIN:
Sudor
Sebo
Queratina
Cera
METABLICA: Vit D
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
68. 3.PATOLOGA DE LA PIEL
69. Definiciones de los trminos macroscpicos
Mcula. Coloracin 5mm.
Ppula, lesin elevada cupuliforme 5mm.
Vescula: Rellena de lquido 5mm.
Pstula = Lleno de pus
Roncha = lesin elevada, pruriginosa, transitoria, con eritema
Escama = Placa cornea seca (queratinizacin anormal)
Excoriacin = Rotura de dermis, puntiformes.
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
70. LESIONES ELEMENTALES PRIMARIAS
DE LA COLORACIN
MACULA ERITEMATOSA
ANGIOMA
MACULA PURPREA
TELANGIECTASIA
MCULA HIPERCRMICA
MACULA HIPOCRMICA
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
71. Mcula pigmentaria hipercrmica
Mcula pigmentaria hipocrmica
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
72. LESIONES ELEMENTALES PRIMARIAS
SLIDAS
PPULA
PLACA
RONCHA O HABN
NDULO
TUMOR
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
73. MCULAS ERITEMATOSAS
Mancha rojiza de origen vascular.
Si aparecen simultneamente hablamos de exantema.
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
74. MCULAS PURPREAS
TELANGIECTASIAS
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
75. LESIONES ELEMENTALES PRIMARIAS
LESIONES AMPOLLOSAS
VESCULA
AMPOLLA
PSTULA
QUISTE
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
76. 1.Mcula. 2. Roncha.3. Ndulo. 4.Tumor
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
77. VESCULAS
AMPOLLAS
PSTULAS
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
78. LESIONES ELEMENTALES SECUNDARIAS
EROSIN
EXCORIACIN
FISURA O RGADE
LCERA
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
79. LESIONES POR MODIFICACIN DE LESIONES PRIMITIVAS
ESCAMA
COSTRA
ESCARA
ATROFIA
ESCLEROSIS
CICATRIZ
LIQUENIFICACIN
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
80. Trminos microscpicos
Hiperqueratosis = Engrosamiento corneo
Paraqueratosis = Ncleos
Ortoqueratosis = Sin ncleos
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
81. Hipergranulosis = Hiperplasia granular Friccin
Acantosis = Hiperplasia espinosa.
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
82. Espongiosis = Edema intercelular.
Hinchazn hidrpica (balloning)= Edema intracelular, virus.
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
83. Papilomatosis = Elevacin irregular en superficie.
Disqueratosis = Queratinizacin anormal.
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
84. Acantolisis = Prdida de uniones intercelulares
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
85. Exocitosis = Clulas inflamatorias intraepidrmicas.
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
86. Erosin = Prdida incompleta de la epidermis.
Ulceracin = Prdida completa de piel
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
87. Vacuolizacin = Vacuolas, generalmente capa basal.
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
88. Lentiginoso = Proliferacin melanocticalineal
Patologa estructural y funcional de Robbins, 8 ed, 2010
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
89. INFECCIONES CUTNEAS
90. INFECCIONES BACTERIANAS -- PIODERMA
Infeccin cutnea bacteriana
IMPTIGO
Contagioso
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
99. Buloso
Sx piel escaldada (Ritter)
Ectima = Imptigo contagioso ulcerado
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
109. ERISIPELA
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
114. FASCIITISNECROSANTE
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
119. TUBERCULOSIS
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
126. Variantes
Primaria
Lpus vulgar
Verrucosa cutnea
Miliar cutnea
Escrofuloderma
Goma tuberculoso
Micobacterias no tuberculosas
micobacterias
136. LEPRA
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
144. Lepromatosa
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
150. Tuberculoide
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
154. Actinomicosis
Botriomicosis
de bacterias
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
162. HERPES
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
169. VERRUGA VIRAL
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
177. Hallazgos patolgicos:
Acantosis papilomatosa
Coilocitosis
Hipergranulosis
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
178. CMV
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
182. MOLUSCO
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
184. HIV
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
187. SFILIS
Primaria
Chancro erosin, infiltrado plasmacitario.
Endarteritis obliterante
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
188. Tinciones de plata = Warthin-Starry
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
189. Secundaria
Varios patrones
Hiperplasia psoriasiforme con dermatitis vacuolar de
interfase
Infiltrado plasmacitario.
Endarteritis obliterante
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
190. LEISHMANIASIS
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
195. ESCABIOSIS
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
199. LARVA MIGRANS CUTNEA
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
204. MORDEDURA DE ARTRPODOS
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005
207. OTROS
BarnhillsDermatopathology, 4 ed, 2008
LeversHistopathology of theskin 9 ed, 2005