Biomecânica - Aula 5

8/16/2019 Biomecânica - Aula 5

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Biomecânica

Prof. Dr. Fernando Borges


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Controle do Remodelamento

– Mecanismo Hormonal que mantem a homeostase

de cálcio no sangue

–

Forças mecânicas e gravitacionais atuam noesqueleto

Homeostase do Remodelamento

M i H l


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Mecanismo Hormonal

•

Aumento de Ca2+ no sangue

estimula a

tireóide a liberarcalcitonina

• Calcitonina

estimula adeposição de sais

de cálcio

M i H l


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Mecanismo Hormonal

• Queda de Ca2+

no sanguesinaliza para as paratireóides

liberarem PTH• PTH sinaliza

aos osteoclastos para degradarmatriz óssea eliberar Ca2+ para o sangue


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National Institute of Health - NIH. Consensus Statement. Osteoporosis prevention, diagnosis, and therapy. Jama. 2001 Feb 14;285(6):785-95

3()$*#*%*($

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Resistência óssea comprometida predispondo a um aumento

do risco de fratura.

• Resistência óssea = integração entre densidade mineral óssea

(DMO) e qualidade óssea.


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• A maioria das fraturas vertebrais sãoassintomáticas

•

Apenas 1/3 a 1/4 das fraturasvertebrais são diagnosticadasclinicamente

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Biomecânica - Aula 5

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